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» Directionality in protein fold prediction
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BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
A hybrid approach to protein folding problem integrating constraint programming with local search
Background: The protein folding problem remains one of the most challenging open problems in computational biology. Simplified models in terms of lattice structure and energy func...
Abu Zafer M. Dayem Ullah, Kathleen Steinhöfel
ICASSP
2007
IEEE
15 years 4 months ago
Protein Fold Recognition using Residue-Based Alignments of Sequence and Secondary Structure
Protein structure prediction aims to determine the three-dimensional structure of proteins form their amino acid sequences. When a protein does not have similarity (homology) to a...
Zafer Aydin, Hakan Erdogan, Yucel Altunbasak
100
Voted
BMCBI
2008
154views more  BMCBI 2008»
14 years 9 months ago
Sequence based residue depth prediction using evolutionary information and predicted secondary structure
Background: Residue depth allows determining how deeply a given residue is buried, in contrast to the solvent accessibility that differentiates between buried and solvent-exposed ...
Hua Zhang, Tuo Zhang, Ke Chen 0003, Shiyi Shen, Ji...
CSB
2004
IEEE
177views Bioinformatics» more  CSB 2004»
15 years 1 months ago
High-Throughput 3D Structural Homology Detection via NMR Resonance Assignment
One goal of the structural genomics initiative is the identification of new protein folds. Sequence-based structural homology prediction methods are an important means for priorit...
Christopher James Langmead, Bruce Randall Donald
GCB
2003
Springer
164views Biometrics» more  GCB 2003»
15 years 2 months ago
Integrative machine learning approach for multi-class SCOP protein fold classification
: Classification and prediction of protein structure has been a central research theme in structural bioinformatics. Due to the imbalanced distribution of proteins over multi SCOP ...
Aik Choon Tan, David Gilbert, Yves Deville