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» Directionality in protein fold prediction
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BMCBI
2008
128views more  BMCBI 2008»
14 years 9 months ago
Pairwise covariance adds little to secondary structure prediction but improves the prediction of non-canonical local structure
Background: Amino acid sequence probability distributions, or profiles, have been used successfully to predict secondary structure and local structure in proteins. Profile models ...
Christopher Bystroff, Bobbie-Jo M. Webb-Robertson
DMKD
2003
ACM
110views Data Mining» more  DMKD 2003»
15 years 2 months ago
Weave amino acid sequences for protein secondary structure prediction
Given a known protein sequence, predicting its secondary structure can help understand its three-dimensional (tertiary) structure, i.e., the folding. In this paper, we present an ...
Xiaochun Yang, Bin Wang
72
Voted
BMCBI
2004
111views more  BMCBI 2004»
14 years 9 months ago
The Hotdog fold: wrapping up a superfamily of thioesterases and dehydratases
Background: The Hotdog fold was initially identified in the structure of Escherichia coli FabA and subsequently in 4-hydroxybenzoyl-CoA thioesterase from Pseudomonas sp. strain CB...
Shane C. Dillon, Alex Bateman
76
Voted
CANDC
2006
ACM
14 years 9 months ago
Hydrophobic collapse in (in silico) protein folding
A model of hydrophobic collapse, which is treated as the driving force for protein folding, is presented. This model is the superposition of three models commonly used in protein ...
Michal Brylinski, Leszek Konieczny, Irena Roterman
BMCBI
2002
81views more  BMCBI 2002»
14 years 9 months ago
Species-specific protein sequence and fold optimizations
Background: An organism's ability to adapt to its particular environmental niche is of fundamental importance to its survival and proliferation. In the largest study of its k...
Michel Dumontier, Katerina Michalickova, Christoph...