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» Directionality in protein fold prediction
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BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
A high level interface to SCOP and ASTRAL implemented in Python
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
James A. Casbon, Gavin E. Crooks, Mansoor A. S. Sa...
BMCBI
2004
208views more  BMCBI 2004»
14 years 9 months ago
Using 3D Hidden Markov Models that explicitly represent spatial coordinates to model and compare protein structures
Background: Hidden Markov Models (HMMs) have proven very useful in computational biology for such applications as sequence pattern matching, gene-finding, and structure prediction...
Vadim Alexandrov, Mark Gerstein
RECOMB
2005
Springer
15 years 10 months ago
Recognition of Binding Patterns Common to a Set of Protein Structures
We present a novel computational method, MultiBind, for recognition of binding patterns common to a set of protein structures. It is the first method which performs a multiple alig...
Maxim Shatsky, Alexandra Shulman-Peleg, Ruth Nussi...
BIBM
2010
IEEE
156views Bioinformatics» more  BIBM 2010»
14 years 7 months ago
Truncation of protein sequences for fast profile alignment with application to subcellular localization
We have recently found that the computation time of homology-based subcellular localization can be substantially reduced by aligning profiles up to the cleavage site positions of s...
Man-Wai Mak, Wei Wang, Sun-Yuan Kung
BMCBI
2011
14 years 4 months ago
Classification of viral zoonosis through receptor pattern analysis
Background: Viral zoonosis, the transmission of a virus from its primary vertebrate reservoir species to humans, requires ubiquitous cellular proteins known as receptor proteins. ...
Se-Eun Bae, Hyeon Seok Son