One of the most remarkable properties of enzyme-substrate binding is the high substrate specificity among homologous enzymes. Identification of regions in enzymes that play an imp...
Gong-Xin Yu, Byung-Hoon Park, Praveen Chandramohan...
Background: Relative isotope abundance quantification, which can be used for peptide identification and differential peptide quantification, plays an important role in liquid chro...
William H. Haskins, Konstantinos Petritis, Jianqiu...
Background: Incorrectly annotated sequence data are becoming more commonplace as databases increasingly rely on automated techniques for annotation. Hence, there is an urgent need...
Abstract. Recent advances in high-throughput experimental techniques have enabled the production of a wealth of protein interaction data, rich in both quantity and variety. While t...
Allister Bernard, David S. Vaughn, Alexander J. Ha...
High-throughput methods can directly detect the set of interacting proteins in yeast but the results are often incomplete and exhibit high false positive and false negative rates....