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» Directionality in protein fold prediction
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BMCBI
2007
102views more  BMCBI 2007»
14 years 9 months ago
FlexOracle: predicting flexible hinges by identification of stable domains
Background: Protein motions play an essential role in catalysis and protein-ligand interactions, but are difficult to observe directly. A substantial fraction of protein motions i...
Samuel Flores, Mark Gerstein
ISMB
1996
14 years 11 months ago
A Knowledge-Based Method for Protein Structure Refinement and Prediction
The native conformation of a protein, in a given environment, is determined entirely by the various interatomic interactions dictated by the amino acid sequence (1-3). We describe...
Shankar Subramaniam, David K. Tcheng, James M. Fen...
BIOCOMP
2006
14 years 11 months ago
A Multi-strategy Approach to Protein Structural Alphabet Design
- The search for structural similarity among proteins can provide valuable insights into their functional mechanisms and their functional relationships. Though the protein 1D seque...
Shih-Yen Ku, Yuh-Jyh Hu
AE
2005
Springer
15 years 3 months ago
Incorporating Knowledge of Secondary Structures in a L-System-Based Encoding for Protein Folding
An encoding scheme for protein folding on lattice models, inspired by parametric L-systems, was proposed. The encoding incorporates problem domain knowledge in the form of predesig...
Gabriela Ochoa, Gabi Escuela, Natalio Krasnogor
JUCS
2010
104views more  JUCS 2010»
14 years 8 months ago
Investigating a Correlation between Subcellular Localization and Fold of Proteins
: When considering the prediction of a structural class for a protein as a classification problem, usually a classifier is based on a feature vector x ∈ Rn , where the features...
Johannes Aßfalg, Jing Gong, Hans-Peter Krieg...