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» Directionality in protein fold prediction
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BMCBI
2011
14 years 1 months ago
Biomarker Discovery and Redundancy Reduction towards Classification using a Multi-factorial MALDI-TOF MS T2DM Mouse Model Datase
Background: Diabetes like many diseases and biological processes is not mono-causal. On the one hand multifactorial studies with complex experimental design are required for its c...
Chris Bauer, Frank Kleinjung, Celia J. Smith, Mark...
BMCBI
2007
165views more  BMCBI 2007»
14 years 9 months ago
Ab initio identification of human microRNAs based on structure motifs
Background: MicroRNAs (miRNAs) are short, non-coding RNA molecules that are directly involved in post-transcriptional regulation of gene expression. The mature miRNA sequence bind...
Markus Brameier, Carsten Wiuf
SDM
2008
SIAM
139views Data Mining» more  SDM 2008»
14 years 11 months ago
Maximal Quasi-Bicliques with Balanced Noise Tolerance: Concepts and Co-clustering Applications
The rigid all-versus-all adjacency required by a maximal biclique for its two vertex sets is extremely vulnerable to missing data. In the past, several types of quasi-bicliques ha...
Jinyan Li, Kelvin Sim, Guimei Liu, Limsoon Wong
ML
2011
ACM
308views Machine Learning» more  ML 2011»
14 years 4 months ago
Relational information gain
Abstract. Type Extension Trees (TET) have been recently introduced as an expressive representation language allowing to encode complex combinatorial features of relational entities...
Marco Lippi, Manfred Jaeger, Paolo Frasconi, Andre...
BMCBI
2010
152views more  BMCBI 2010»
14 years 9 months ago
A high-throughput de novo sequencing approach for shotgun proteomics using high-resolution tandem mass spectrometry
Background: High-resolution tandem mass spectra can now be readily acquired with hybrid instruments, such as LTQ-Orbitrap and LTQ-FT, in high-throughput shotgun proteomics workflo...
Chongle Pan, Byung-Hoon Park, William H. McDonald,...