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BMCBI
2010
135views more  BMCBI 2010»
14 years 12 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
GECCO
2006
Springer
161views Optimization» more  GECCO 2006»
15 years 3 months ago
Innovization: innovating design principles through optimization
This paper introduces a new design methodology (we call it "innovization") in the context of finding new and innovative design principles by means of optimization techni...
Kalyanmoy Deb, Aravind Srinivasan
CHI
1998
ACM
15 years 4 months ago
Patterns of Change in Design Metaphor: A Case Study
Although design metaphors play an important role in many software projects, their influence on system functionality, project methodology and the interactions among members of the ...
William A. Stubblefield
DAC
2006
ACM
15 years 5 months ago
Automated design of pin-constrained digital microfluidic arrays for lab-on-a-chip applications*
Microfluidics-based biochips, also referred to as lab-on-a-chip (LoC), are devices that integrate fluid-handling functions such as sample preparation, analysis, separation, and de...
William L. Hwang, Fei Su, Krishnendu Chakrabarty
ASWEC
2007
IEEE
15 years 6 months ago
A Formal Model of Service-Oriented Design Structure
—Service-Oriented Computing (SOC) is an emerging paradigm for developing software systems that employ services. Presently there is already much research effort in the areas of se...
Mikhail Perepletchikov, Caspar Ryan, Keith Frampto...