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88
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NAR
2011
215views Computer Vision» more  NAR 2011»
14 years 1 months ago
dbCRID: a database of chromosomal rearrangements in human diseases
Chromosomal rearrangement (CR) events result from abnormal breaking and rejoining of the DNA molecules, or from crossing-over between repetitive DNA sequences, and they are involv...
Fanlou Kong, Jing Zhu, Jun Wu, Jianjian Peng, Ying...
126
Voted
BMCBI
2007
194views more  BMCBI 2007»
14 years 10 months ago
Kernel-imbedded Gaussian processes for disease classification using microarray gene expression data
Background: Designing appropriate machine learning methods for identifying genes that have a significant discriminating power for disease outcomes has become more and more importa...
Xin Zhao, Leo Wang-Kit Cheung
114
Voted
BMCBI
2010
196views more  BMCBI 2010»
14 years 7 months ago
Content-based microarray search using differential expression profiles
Background: With the expansion of public repositories such as the Gene Expression Omnibus (GEO), we are rapidly cataloging cellular transcriptional responses to diverse experiment...
Jesse M. Engreitz, Alexander A. Morgan, Joel Dudle...
91
Voted
BMCBI
2010
154views more  BMCBI 2010»
14 years 10 months ago
Candidate gene prioritization by network analysis of differential expression using machine learning approaches
Background: Discovering novel disease genes is still challenging for diseases for which no prior knowledge - such as known disease genes or disease-related pathways - is available...
Daniela Nitsch, Joana P. Gonçalves, Fabian ...
84
Voted
BMCBI
2008
120views more  BMCBI 2008»
14 years 10 months ago
A protein interaction based model for schizophrenia study
Background: Schizophrenia is a complex disease with multiple factors contributing to its pathogenesis. In addition to environmental factors, genetic factors may also increase susc...
Pei-Chun Hsu, Ueng-Cheng Yang, Kuan-Hui Shih, Chih...