A central issue in molecular biology is understanding the regulatory mechanisms that control gene expression. The recent flood of genomic and postgenomic data opens the way for co...
Background: Genome wide microarray studies have the potential to unveil novel disease entities. Clinically homogeneous groups of patients can have diverse gene expression profiles...
Clustering has been one of the most popular approaches used in gene expression data analysis. A clustering method is typically used to partition genes according to their similarity...
If all features causing heterogeneity were observed, a mixture of experts approach (Jacobs et al., 1991) is likely to be superior to using a single model. When unobserved or very n...
Identifying information-rich subsets in high-dimensional spaces and representing them as order revealing patterns (or trends) is an important and challenging research problem in m...