Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
Abstract. In this paper, we introduce a new approach for mining regulatory interactions between genes in microarray time series studies. A number of preprocessing steps transform t...
Michael Egmont-Petersen, Wim de Jonge, Arno Siebes
Protein complexes are fundamental for understanding principles of cellular organizations. Accurate and fast protein complex prediction from the PPI networks of increasing sizes ca...
Hon Nian Chua, Kang Ning, Wing-Kin Sung, Hon Wai L...
Background: Synthetic lethality experiments identify pairs of genes with complementary function. More direct functional associations (for example greater probability of membership...
Background: Most proteins function by interacting with other molecules. Their interaction interfaces are highly conserved throughout evolution to avoid undesirable interactions th...
Sungsam Gong, Changbum Park, Hansol Choi, Junsu Ko...