Background: An important class of interaction switches for biological circuits and disease pathways are short binding motifs. However, the biological experiments to find these bin...
Soon-Heng Tan, Hugo Willy, Wing-Kin Sung, See-Kion...
Background: Extracting Protein-Protein Interactions (PPI) from research papers is a way of translating information from English to the language used by the databases that store th...
Background: Large-scale compilation of gene expression microarray datasets across diverse biological phenotypes provided a means of gathering a priori knowledge in the form of ide...
We develop a new framework for inferring models of transcriptional regulation. The models in this approach, which we call physical models, are constructed on the basis of verifiab...
Background: In gene expression analysis, statistical tests for differential gene expression provide lists of candidate genes having, individually, a sufficiently low p-value. Howe...
Stefano Moretti, Danitsja van Leeuwen, Hans Gmuend...