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NAR
2010
194views more  NAR 2010»
14 years 4 months ago
AltAnalyze and DomainGraph: analyzing and visualizing exon expression data
Alternative splicing is an important mechanism for increasing protein diversity. However, its functional effects are largely unknown. Here, we present our new software workflow co...
Dorothea Emig, Nathan Salomonis, Jan Baumbach, Tho...
BMCBI
2008
170views more  BMCBI 2008»
14 years 9 months ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
BMCBI
2005
189views more  BMCBI 2005»
14 years 9 months ago
Quantitative inference of dynamic regulatory pathways via microarray data
Background: The cellular signaling pathway (network) is one of the main topics of organismic investigations. The intracellular interactions between genes in a signaling pathway ar...
Wen-Chieh Chang, Chang-Wei Li, Bor-Sen Chen
BMCBI
2005
95views more  BMCBI 2005»
14 years 9 months ago
Commensurate distances and similar motifs in genetic congruence and protein interaction networks in yeast
Background: In a genetic interaction, the phenotype of a double mutant differs from the combined phenotypes of the underlying single mutants. When the single mutants have no growt...
Ping Ye, Brian D. Peyser, Forrest A. Spencer, Joel...
BMCBI
2005
124views more  BMCBI 2005»
14 years 9 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...