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» Discovery of Regulatory Connections in Microarray Data
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BMCBI
2010
219views more  BMCBI 2010»
13 years 1 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
BMCBI
2005
201views more  BMCBI 2005»
13 years 6 months ago
Principal component analysis for predicting transcription-factor binding motifs from array-derived data
Background: The responses to interleukin 1 (IL-1) in human chondrocytes constitute a complex regulatory mechanism, where multiple transcription factors interact combinatorially to...
Yunlong Liu, Matthew P. Vincenti, Hiroki Yokota
ISMB
2000
13 years 7 months ago
Genes, Themes, and Microarrays: Using Information Retrieval for Large-Scale Gene Analysis
The immensevolumeof data resulting from DNAmicroarray experiments, accompaniedby an increase in the numberof publications discussing gene-related discoveries, presents a majordata...
Hagit Shatkay, Stephen Edwards, W. John Wilbur, Ma...
RECOMB
2006
Springer
14 years 6 months ago
Identification and Evaluation of Functional Modules in Gene Co-expression Networks
Abstract. Identifying gene functional modules is an important step towards elucidating gene functions at a global scale. In this paper, we introduce a simple method to construct ge...
Jianhua Ruan, Weixiong Zhang
BMCBI
2010
172views more  BMCBI 2010»
13 years 6 months ago
Inferring gene regression networks with model trees
Background: Novel strategies are required in order to handle the huge amount of data produced by microarray technologies. To infer gene regulatory networks, the first step is to f...
Isabel A. Nepomuceno-Chamorro, Jesús S. Agu...