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» Disease Modeling Using Evolved Discriminate Function
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BMCBI
2008
149views more  BMCBI 2008»
14 years 12 months ago
Evolution of biological sequences implies an extreme value distribution of type I for both global and local pairwise alignment s
Background: Confidence in pairwise alignments of biological sequences, obtained by various methods such as Blast or Smith-Waterman, is critical for automatic analyses of genomic d...
Olivier Bastien, Eric Maréchal
105
Voted
BMCBI
2008
154views more  BMCBI 2008»
14 years 12 months ago
GeNESiS: gene network evolution simulation software
Background: There has been a lot of interest in recent years focusing on the modeling and simulation of Gene Regulatory Networks (GRNs). However, the evolutionary mechanisms that ...
Anton Kratz, Masaru Tomita, Arun Krishnan
CIKM
2004
Springer
15 years 5 months ago
Hierarchical document categorization with support vector machines
Automatically categorizing documents into pre-defined topic hierarchies or taxonomies is a crucial step in knowledge and content management. Standard machine learning techniques ...
Lijuan Cai, Thomas Hofmann
BMCBI
2010
163views more  BMCBI 2010»
14 years 12 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek
GECCO
2008
Springer
154views Optimization» more  GECCO 2008»
15 years 25 days ago
Automated shape composition based on cell biology and distributed genetic programming
Motivated by the ability of living cells to form specific shapes and structures, we present a computational approach using distributed genetic programming to discover cell-cell i...
Linge Bai, Manolya Eyiyurekli, David E. Breen