Background: Large-scale sequencing of entire genomes has ushered in a new age in biology. One of the next grand challenges is to dissect the cellular networks consisting of many i...
Background: Innovative extensions of (M) ANOVA gain common ground for the analysis of designed metabolomics experiments. ASCA is such a multivariate analysis method; it has succes...
Daniel J. Vis, Johan A. Westerhuis, Age K. Smilde,...
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
Evolving large phenotypes remains nowadays a problem due to the combinatorial explosion of the search space. Seeking better scalability and inspired by the development of biologica...
Cellular automata (CA) are highly parallel and discrete dynamical systems, whose behavior is completely specified in terms of a local relation. They were successfully applied for s...