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BMCBI
2007
152views more  BMCBI 2007»
15 years 1 months ago
Recodon: Coalescent simulation of coding DNA sequences with recombination, migration and demography
Background: Coalescent simulations have proven very useful in many population genetics studies. In order to arrive to meaningful conclusions, it is important that these simulation...
Miguel Arenas, David Posada
BMCBI
2007
148views more  BMCBI 2007»
15 years 1 months ago
Computation of significance scores of unweighted Gene Set Enrichment Analyses
Background: Gene Set Enrichment Analysis (GSEA) is a computational method for the statistical evaluation of sorted lists of genes or proteins. Originally GSEA was developed for in...
Andreas Keller, Christina Backes, Hans-Peter Lenho...
BMCBI
2007
177views more  BMCBI 2007»
15 years 1 months ago
Biowep: a workflow enactment portal for bioinformatics applications
Background: The huge amount of biological information, its distribution over the Internet and the heterogeneity of available software tools makes the adoption of new data integrat...
Paolo Romano 0001, Ezio Bartocci, Guglielmo Bertol...
JCB
2006
123views more  JCB 2006»
15 years 1 months ago
Reconstructing Ancestral Haplotypes with a Dictionary Model
We propose a dictionary model for haplotypes. According to the model, a haplotype is constructed by randomly concatenating haplotype segments from a given dictionary of segments. ...
Kristin L. Ayers, Chiara Sabatti, Kenneth Lange
JCB
2006
140views more  JCB 2006»
15 years 1 months ago
HAPLOFREQ-Estimating Haplotype Frequencies Efficiently
A commonly used tool in disease association studies is the search for discrepancies between the haplotype distribution in the case and control populations. In order to find this d...
Eran Halperin, Elad Hazan
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