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BMCBI
2006
138views more  BMCBI 2006»
15 years 6 months ago
Determination of strongly overlapping signaling activity from microarray data
Background: As numerous diseases involve errors in signal transduction, modern therapeutics often target proteins involved in cellular signaling. Interpretation of the activity of...
Ghislain Bidaut, Karsten Suhre, Jean-Michel Claver...
BMCBI
2006
103views more  BMCBI 2006»
15 years 6 months ago
Domain-based small molecule binding site annotation
Background: Accurate small molecule binding site information for a protein can facilitate studies in drug docking, drug discovery and function prediction, but small molecule bindi...
Kevin A. Snyder, Howard J. Feldman, Michel Dumonti...
BMCBI
2006
84views more  BMCBI 2006»
15 years 6 months ago
Inferring topology from clustering coefficients in protein-protein interaction networks
Background: Although protein-protein interaction networks determined with high-throughput methods are incomplete, they are commonly used to infer the topology of the complete inte...
Caroline C. Friedel, Ralf Zimmer
CORR
2006
Springer
119views Education» more  CORR 2006»
15 years 6 months ago
An approach to RAID-6 based on cyclic groups of a prime order
As the size of data storing arrays of disks grows, it becomes vital to protect data against double disk failures. An economic way of providing such protection consists of adding tw...
R. Jackson, D. Rumynin, O. Zaboronski
BMCBI
2007
166views more  BMCBI 2007»
15 years 6 months ago
Data handling strategies for high throughput pyrosequencers
Background: New high throughput pyrosequencers such as the 454 Life Sciences GS 20 are capable of massively parallelizing DNA sequencing providing an unprecedented rate of output ...
Gabriele A. Trombetti, Raoul J. P. Bonnal, Ermanno...