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BMCBI
2010
124views more  BMCBI 2010»
15 years 2 months ago
Estimation and efficient computation of the true probability of recurrence of short linear protein sequence motifs in unrelated
Background: Large datasets of protein interactions provide a rich resource for the discovery of Short Linear Motifs (SLiMs) that recur in unrelated proteins. However, existing met...
Norman E. Davey, Richard J. Edwards, Denis C. Shie...
129
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BMCBI
2010
109views more  BMCBI 2010»
15 years 2 months ago
ParallABEL: an R library for generalized parallelization of genome-wide association studies
Background: Genome-Wide Association (GWA) analysis is a powerful method for identifying loci associated with complex traits and drug response. Parts of GWA analyses, especially th...
Unitsa Sangket, Surakameth Mahasirimongkol, Wasun ...
97
Voted
BMCBI
2008
112views more  BMCBI 2008»
15 years 2 months ago
GlycomeDB - integration of open-access carbohydrate structure databases
Background: Although carbohydrates are the third major class of biological macromolecules, after proteins and DNA, there is neither a comprehensive database for carbohydrate struc...
René Ranzinger, Stephan Herget, Thomas Wett...
CN
2008
127views more  CN 2008»
15 years 2 months ago
Decentralized detection of global threshold crossings using aggregation trees
The timely detection that a monitored variable has crossed a given threshold is a fundamental requirement for many network management applications. A challenge is the detection of ...
Fetahi Wuhib, Mads Dam, Rolf Stadler
141
Voted
CORR
2010
Springer
133views Education» more  CORR 2010»
15 years 2 months ago
Scalable, Time-Responsive, Digital, Energy-Efficient Molecular Circuits using DNA Strand Displacement
We propose a novel theoretical biomolecular design to implement any Boolean circuit using the mechanism of DNA strand displacement. The design is scalable: all species of DNA stra...
Ehsan Chiniforooshan, David Doty, Lila Kari, Shinn...