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95
Voted
BMCBI
2008
14 years 10 months ago
2008
Background: Cellular metabolism is one of the most investigated system of biological interactions. While the topological nature of individual reactions and pathways in the network...
BMCBI
2008
14 years 10 months ago
2008
Background: Quantitative characterization of the topological characteristics of protein-protein interaction (PPI) networks can enable the elucidation of biological functional modu...
94
Voted
BMCBI
2010
14 years 10 months ago
2010
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
BMCBI
2008
14 years 10 months ago
2008
Background: Large biological data sets, such as expression profiles, benefit from reduction of random noise. Principal component (PC) analysis has been used for this purpose, but ...
BMCBI
2008
14 years 10 months ago
2008
Background: Accurate annotation of translation initiation sites (TISs) is essential for understanding the translation initiation mechanism. However, the reliability of TIS annotat...