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93
Voted
BMCBI
2006
15 years 24 days ago
2006
Background: In a microarray experiment the difference in expression between genes on the same slide is up to 103 fold or more. At low expression, even a small error in the estimat...
99
Voted
BMCBI
2006
15 years 24 days ago
2006
Background: Benchmarking algorithms in structural bioinformatics often involves the construction of datasets of proteins with given sequence and structural properties. The SCOP da...
112
Voted
BMCBI
2006
15 years 24 days ago
2006
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
118
Voted
BMCBI
2006
15 years 24 days ago
2006
Background: The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Central...
93
Voted
BMCBI
2006
15 years 24 days ago
2006
Background: Publicly accessible EST libraries contain valuable information that can be utilized for studies of tissue-specific gene expression and processing of individual genes. ...