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BMCBI
2007
174views more  BMCBI 2007»
14 years 11 months ago
Normalization method for metabolomics data using optimal selection of multiple internal standards
Background: Success of metabolomics as the phenotyping platform largely depends on its ability to detect various sources of biological variability. Removal of platform-specific so...
Marko Sysi-Aho, Mikko Katajamaa, Laxman Yetukuri, ...
BMCBI
2007
130views more  BMCBI 2007»
14 years 11 months ago
Requirements and ontology for a G protein-coupled receptor oligomerization knowledge base
Background: G Protein-Coupled Receptors (GPCRs) are a large and diverse family of membrane proteins whose members participate in the regulation of most cellular and physiological ...
Lucy Skrabanek, Marta Murcia, Michel Bouvier, Laks...
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BMCBI
2007
97views more  BMCBI 2007»
14 years 11 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2008
122views more  BMCBI 2008»
14 years 11 months ago
High-throughput bioinformatics with the Cyrille2 pipeline system
Background: Modern omics research involves the application of high-throughput technologies that generate vast volumes of data. These data need to be pre-processed, analyzed and in...
Mark W. E. J. Fiers, Ate van der Burgt, Erwin Date...
BMCBI
2008
144views more  BMCBI 2008»
14 years 11 months ago
PDTD: a web-accessible protein database for drug target identification
Background: Target identification is important for modern drug discovery. With the advances in the development of molecular docking, potential binding proteins may be discovered b...
Zhenting Gao, Honglin Li, Hailei Zhang, Xiaofeng L...