Sciweavers

5804 search results - page 1115 / 1161
» Doing more with less
Sort
View
BMCBI
2010
120views more  BMCBI 2010»
14 years 12 months ago
Estimating true evolutionary distances under rearrangements, duplications, and losses
Background: The rapidly increasing availability of whole-genome sequences has enabled the study of whole-genome evolution. Evolutionary mechanisms based on genome rearrangements h...
Yu Lin, Vaibhav Rajan, Krister M. Swenson, Bernard...
BMCBI
2010
132views more  BMCBI 2010»
14 years 12 months ago
Consistency, comprehensiveness, and compatibility of pathway databases
Background: It is necessary to analyze microarray experiments together with biological information to make better biological inferences. We investigate the adequacy of current bio...
Donny Soh, Difeng Dong, Yike Guo, Limsoon Wong
BMCBI
2008
130views more  BMCBI 2008»
14 years 12 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
BMCBI
2010
132views more  BMCBI 2010»
14 years 12 months ago
Protein network prediction and topological analysis in Leishmania major as a tool for drug target selection
Background: Leishmaniasis is a virulent parasitic infection that causes a worldwide disease burden. Most treatments have toxic side-effects and efficacy has decreased due to the e...
Andrés F. Flórez, Daeui Park, Jong B...
BMCBI
2010
164views more  BMCBI 2010»
14 years 12 months ago
Flexible network reconstruction from relational databases with Cytoscape and CytoSQL
Background: Molecular interaction networks can be efficiently studied using network visualization software such as Cytoscape. The relevant nodes, edges and their attributes can be...
Kris Laukens, Jens Hollunder, Thanh Hai Dang, Geer...
« Prev « First page 1115 / 1161 Last » Next »