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BMCBI
2008
14 years 12 months ago
2008
Background: The expressed sequence tag (EST) methodology is an attractive option for the generation of sequence data for species for which no completely sequenced genome is availa...
109
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BMCBI
2008
14 years 12 months ago
2008
Background: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is...
BMCBI
2007
14 years 12 months ago
2007
Background: The architecture of biological networks has been reported to exhibit high level of modularity, and to some extent, topological modules of networks overlap with known f...
115
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BMCBI
2010
14 years 12 months ago
2010
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
BMCBI
2008
14 years 12 months ago
2008
Background: Over 60% of protein-coding genes in vertebrates express mRNAs that undergo alternative splicing. The resulting collection of transcript isoforms poses significant chal...