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» Domain Identification by Clustering Sequence Alignments
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RECOMB
2006
Springer
14 years 6 months ago
Domain Architecture in Homolog Identification
Homology identification is the first step for many genomic studies. Current methods, based on sequence comparison, can result in a substantial number of mis-assignments due to the ...
Nan Song, R. D. Sedgewick, Dannie Durand
IPPS
2006
IEEE
14 years 13 days ago
A method to improve structural modeling based on conserved domain clusters
—Homology modeling requires an accurate alignment between a query sequence and its homologs with known three-dimensional (3D) information. Current structural modeling techniques ...
Fa Zhang, Lin Xu, Bo Yuan
BIBM
2010
IEEE
144views Bioinformatics» more  BIBM 2010»
13 years 4 months ago
Identification and quantification of abundant species from pyrosequences of 16S rRNA by consensus alignment
16S rRNA gene profiling has recently been boosted by the development of pyrosequencing methods. A common analysis is to group pyrosequences into Operational Taxonomic Units (OTUs),...
Yuzhen Ye
BMCBI
2006
78views more  BMCBI 2006»
13 years 6 months ago
Subfamily logos: visualization of sequence deviations at alignment positions with high information content
Background: Recognition of relevant sequence deviations can be valuable for elucidating functional differences between protein subfamilies. Interesting residues at highly conserve...
Eric Beitz
BMCBI
2008
114views more  BMCBI 2008»
13 years 6 months ago
Indel PDB: A database of structural insertions and deletions derived from sequence alignments of closely related proteins
Background: Insertions and deletions (indels) represent a common type of sequence variations, which are less studied and pose many important biological questions. Recent research ...
Michael Hsing, Artem Cherkasov