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BMCBI
2008
107views more  BMCBI 2008»
15 years 3 months ago
GPR17: Molecular modeling and dynamics studies of the 3-D structure and purinergic ligand binding features in comparison with P2
Background: GPR17 is a G-protein-coupled receptor located at intermediate phylogenetic position between two distinct receptor families: the P2Y and CysLT receptors for extracellul...
Chiara Parravicini, Graziella Ranghino, Maria P. A...
136
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JCB
2006
144views more  JCB 2006»
15 years 3 months ago
Modeling Virus Self-Assembly Pathways: Avoiding Dynamics Using Geometric Constraint Decomposition
We develop a model for elucidating the assembly pathways by which an icosahedral viral shell forms from 60 identical constituent protein monomers. This poorly understood process a...
Meera Sitharam, Mavis Agbandje-Mckenna
107
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HCI
2007
15 years 4 months ago
Modeling Human Bipedal Navigation in a Dynamic Three Dimensional Virtual Environment
The current research sought to construct a computational model of human navigation for virtual three dimensional environments. The model was implemented within the ACT-R cognitive ...
Mark D. Thomas, Daniel W. Carruth, Bryan Robbins, ...
118
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JCC
2007
69views more  JCC 2007»
15 years 3 months ago
Discrimination of dynamical system models for biological and chemical processes
In technical chemistry, systems biology and biotechnology, the construction of predictive models has become an essential step in process design and product optimization. Accurate ...
Sönke Lorenz, Elmar Diederichs, Regina Telgma...
112
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WSC
2004
15 years 4 months ago
Dynamic Radiation Dose Visualization in Discrete-Event Nuclear Facility Simulation Models
To improve its process modeling capabilities, Los Alamos has worked toward integrating dose modeling tools with advanced discrete-event simulation tools. To date, dose information...
George Tompkins, Drew E. Kornreich, Robert Y. Park...