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ALMOB
2008
160views more  ALMOB 2008»
15 years 4 months ago
Syntenator: Multiple gene order alignments with a gene-specific scoring function
Background: Identification of homologous regions or conserved syntenies across genomes is one crucial step in comparative genomics. This task is usually performed by genome alignm...
Christian Rödelsperger, Christoph Dieterich
139
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BMCBI
2007
140views more  BMCBI 2007»
15 years 4 months ago
Investigations into the relationship between feedback loops and functional importance of a signal transduction network based on
Background: A number of studies on biological networks have been carried out to unravel the topological characteristics that can explain the functional importance of network nodes...
Yung-Keun Kwon, Sun Shim Choi, Kwang-Hyun Cho
BMCBI
2008
118views more  BMCBI 2008»
15 years 4 months ago
Drug interaction prediction using ontology-driven hypothetical assertion framework for pathway generation followed by numerical
Background: In accordance with the increasing amount of information concerning individual differences in drug response and molecular interaction, the role of in silico prediction ...
Takeshi Arikuma, Sumi Yoshikawa, Ryuzo Azuma, Kent...
BMCBI
2006
129views more  BMCBI 2006»
15 years 4 months ago
EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
Laila A. Nahum, Matthew T. Reynolds, Zhengyuan O. ...
147
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BMCBI
2006
150views more  BMCBI 2006»
15 years 4 months ago
CGAT: a comparative genome analysis tool for visualizing alignments in the analysis of complex evolutionary changes between clos
Background: The recent accumulation of closely related genomic sequences provides a valuable resource for the elucidation of the evolutionary histories of various organisms. Howev...
Ikuo Uchiyama, Toshio Higuchi, Ichizo Kobayashi