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BMCBI
2010
105views more  BMCBI 2010»
15 years 1 months ago
Effects of scanning sensitivity and multiple scan algorithms on microarray data quality
Background: Maximizing the utility of DNA microarray data requires optimization of data acquisition through selection of an appropriate scanner setting. To increase the amount of ...
Andrew Williams, Errol M. Thomson
BMCBI
2010
141views more  BMCBI 2010»
15 years 1 months ago
Computing and visually analyzing mutual information in molecular co-evolution
Background: Selective pressure in molecular evolution leads to uneven distributions of amino acids and nucleotides. In fact one observes correlations among such constituents due t...
Sebastian Bremm, Tobias Schreck, Patrick Boba, Ste...
BIOSYSTEMS
2007
107views more  BIOSYSTEMS 2007»
15 years 1 months ago
Calcium signalling in astrocytes and modulation of neural activity
Up to few years ago astrocytes have been considered as passive elements of brain, providing structural and metabolic support to the neurons, but playing little role in information...
Angelo Di Garbo, Michele Barbi, Santi Chillemi, Su...
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BMCBI
2010
160views more  BMCBI 2010»
15 years 1 months ago
Identification of functional hubs and modules by converting interactome networks into hierarchical ordering of proteins
Background: Protein-protein interactions play a key role in biological processes of proteins within a cell. Recent high-throughput techniques have generated protein-protein intera...
Young-Rae Cho, Aidong Zhang
BMCBI
2010
152views more  BMCBI 2010»
15 years 1 months ago
Comparative study of discretization methods of microarray data for inferring transcriptional regulatory networks
Background: Microarray data discretization is a basic preprocess for many algorithms of gene regulatory network inference. Some common discretization methods in informatics are us...
Yong Li, Lili Liu, Xi Bai, Hua Cai, Wei Ji, Dianji...
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