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172
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BMCBI
2006
15 years 3 months ago
2006
Background: Microarrays are routinely used to assess mRNA transcript levels on a genome-wide scale. Large amount of microarray datasets are now available in several databases, and...
155
Voted
BMCBI
2006
15 years 3 months ago
2006
Background: The small sample sizes often used for microarray experiments result in poor estimates of variance if each gene is considered independently. Yet accurately estimating v...
159
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BMCBI
2006
15 years 3 months ago
2006
Background: We consider the problem of parameter estimation (model calibration) in nonlinear dynamic models of biological systems. Due to the frequent ill-conditioning and multi-m...
139
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BMCBI
2006
15 years 3 months ago
2006
Background: The recent accumulation of closely related genomic sequences provides a valuable resource for the elucidation of the evolutionary histories of various organisms. Howev...
120
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CSDA
2006
15 years 3 months ago
2006
We explore different approaches for performing hypothesis tests on the shape of a mean function by developing general methodologies both, for the often assumed, i.i.d. error struc...