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BMCBI
2010
109views more  BMCBI 2010»
14 years 11 months ago
Application of machine learning methods to histone methylation ChIP-Seq data reveals H4R3me2 globally represses gene expression
Background: In the last decade, biochemical studies have revealed that epigenetic modifications including histone modifications, histone variants and DNA methylation form a comple...
Xiaojiang Xu, Stephen Hoang, Marty W. Mayo, Stefan...
BMCBI
2007
112views more  BMCBI 2007»
14 years 11 months ago
Integrated olfactory receptor and microarray gene expression databases
Background: Gene expression patterns of olfactory receptors (ORs) are an important component of the signal encoding mechanism in the olfactory system since they determine the inte...
Nian Liu, Chiquito J. Crasto, Minghong Ma
BMCBI
2007
181views more  BMCBI 2007»
14 years 11 months ago
Versatile annotation and publication quality visualization of protein complexes using POLYVIEW-3D
Background: Macromolecular visualization as well as automated structural and functional annotation tools play an increasingly important role in the post-genomic era, contributing ...
Aleksey A. Porollo, Jaroslaw Meller
BMCBI
2008
163views more  BMCBI 2008»
14 years 11 months ago
Nuclear staining and relative distance for quantifying epidermal differentiation in biomarker expression profiling
Background: The epidermal physiology results from a complex regulated homeostasis of keratinocyte proliferation, differentiation and death and is tightly regulated by a specific p...
Thora Pommerencke, Thorsten Steinberg, Hartmut Dic...
BMCBI
2008
79views more  BMCBI 2008»
14 years 11 months ago
In silico docking of urokinase plasminogen activator and integrins
Background: Urokinase, its receptor and the integrins are functionally associated and involved in regulation of cell signaling, migration, adhesion and proliferation. No structura...
Bernard Degryse, Juan Fernández-Recio, Vale...