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BMEI
2008
IEEE
14 years 11 months ago
Clustering of High-Dimensional Gene Expression Data with Feature Filtering Methods and Diffusion Maps
The importance of gene expression data in cancer diagnosis and treatment by now has been widely recognized by cancer researchers in recent years. However, one of the major challen...
Rui Xu, Steven Damelin, Boaz Nadler, Donald C. Wun...
BMCBI
2008
96views more  BMCBI 2008»
14 years 9 months ago
Use of normalization methods for analysis of microarrays containing a high degree of gene effects
Background: High-throughput microarrays are widely used to study gene expression across tissues and developmental stages. Analysis of gene expression data is challenging in these ...
Terri T. Ni, William J. Lemon, Yu Shyr, Tao P. Zho...
BMCBI
2010
170views more  BMCBI 2010»
14 years 9 months ago
Integrative analysis of gene expression and copy number alterations using canonical correlation analysis
Background: With the rapid development of new genetic measurement methods, several types of genetic alterations can be quantified in a high-throughput manner. While the initial fo...
Charlotte Soneson, Henrik Lilljebjörn, Thoas ...
BMCBI
2007
130views more  BMCBI 2007»
14 years 9 months ago
Reproducibility of microarray data: a further analysis of microarray quality control (MAQC) data
Background: Many researchers are concerned with the comparability and reliability of microarray gene expression data. Recent completion of the MicroArray Quality Control (MAQC) pr...
James J. Chen, Huey-miin Hsueh, Robert R. Delongch...
BIBM
2010
IEEE
173views Bioinformatics» more  BIBM 2010»
14 years 7 months ago
Network-based identification of smoking-associated gene signature for lung cancer
This study presents a novel computational approach to identifying a smoking-associated gene signature. The methodology contains the following steps: 1) identifying genes significa...
Ying-Wooi Wan, Changchang Xiao, Nancy Lan Guo