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BMCBI
2010
130views more  BMCBI 2010»
14 years 9 months ago
Knowledge-guided gene ranking by coordinative component analysis
Background: In cancer, gene networks and pathways often exhibit dynamic behavior, particularly during the process of carcinogenesis. Thus, it is important to prioritize those gene...
Chen Wang, Jianhua Xuan, Huai Li, Yue Wang, Ming Z...
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BMCBI
2006
179views more  BMCBI 2006»
14 years 9 months ago
Accurate and unambiguous tag-to-gene mapping in serial analysis of gene expression
Background: In this study, we present a robust and reliable computational method for tag-togene assignment in serial analysis of gene expression (SAGE). The method relies on curre...
Rodrigo Malig, Cristian Varela, Eduardo Agosin, Fr...
BMCBI
2007
111views more  BMCBI 2007»
14 years 9 months ago
Novel definition files for human GeneChips based on GeneAnnot
Background: Improvements in genome sequence annotation revealed discrepancies in the original probeset/gene assignment in Affymetrix microarray and the existence of differences be...
Francesco Ferrari, Stefania Bortoluzzi, Alessandro...
BMCBI
2008
102views more  BMCBI 2008»
14 years 9 months ago
Response projected clustering for direct association with physiological and clinical response data
Background: Microarray gene expression data are often analyzed together with corresponding physiological response and clinical metadata of biological subjects, e.g. patients'...
Sung-Gon Yi, Taesung Park, Jae K. Lee
BMCBI
2008
135views more  BMCBI 2008»
14 years 9 months ago
Knowledge-guided multi-scale independent component analysis for biomarker identification
Background: Many statistical methods have been proposed to identify disease biomarkers from gene expression profiles. However, from gene expression profile data alone, statistical...
Li Chen, Jianhua Xuan, Chen Wang, Ie-Ming Shih, Yu...