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BMCBI
2010
100views more  BMCBI 2010»
14 years 9 months ago
Trimming of mammalian transcriptional networks using network component analysis
Background: Network Component Analysis (NCA) has been used to deduce the activities of transcription factors (TFs) from gene expression data and the TF-gene binding relationship. ...
Linh M. Tran, Daniel R. Hyduke, James C. Liao
BMCBI
2010
108views more  BMCBI 2010»
14 years 4 months ago
Preferred analysis methods for Affymetrix GeneChips. II. An expanded, balanced, wholly-defined spike-in dataset
Background: Concomitant with the rise in the popularity of DNA microarrays has been a surge of proposed methods for the analysis of microarray data. Fully controlled "spike-i...
Qianqian Zhu, Jeffrey C. Miecznikowski, Marc S. Ha...
BMCBI
2010
110views more  BMCBI 2010»
14 years 9 months ago
TimeDelay-ARACNE: Reverse engineering of gene networks from time-course data by an information theoretic approach
Background: One of main aims of Molecular Biology is the gain of knowledge about how molecular components interact each other and to understand gene function regulations. Using mi...
Pietro Zoppoli, Sandro Morganella, Michele Ceccare...
NAR
2010
111views more  NAR 2010»
14 years 4 months ago
Babelomics: an integrative platform for the analysis of transcriptomics, proteomics and genomic data with advanced functional pr
Babelomics is a response to the growing necessity of integrating and analyzing different types of genomic data in an environment that allows an easy functional interpretation of t...
Ignacio Medina, José Carbonell, Luis Pulido...
BIBE
2004
IEEE
160views Bioinformatics» more  BIBE 2004»
15 years 1 months ago
A Time Series Analysis of Microarray Data
As the capture and analysis of single-time-point microarray expression data becomes routine, investigators are turning to time-series expression data to investigate complex gene r...
Selnur Erdal, Ozgur Ozturk, David L. Armbruster, H...