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BMCBI
2008
129views more  BMCBI 2008»
14 years 9 months ago
A unified approach to false discovery rate estimation
Background: False discovery rate (FDR) methods play an important role in analyzing highdimensional data. There are two types of FDR, tail area-based FDR and local FDR, as well as ...
Korbinian Strimmer
BMCBI
2006
125views more  BMCBI 2006»
14 years 9 months ago
Evaluating different methods of microarray data normalization
Background: With the development of DNA hybridization microarray technologies, nowadays it is possible to simultaneously assess the expression levels of thousands to tens of thous...
André Fujita, João Ricardo Sato, Leo...
CCE
2005
14 years 9 months ago
Selecting maximally informative genes
Microarray experiments are emerging as one of the main driving forces in modern biology. By allowing the simultaneous monitoring of the expression of the entire genome for a given...
Ioannis P. Androulakis
BMCBI
2004
144views more  BMCBI 2004»
14 years 9 months ago
PASBio: predicate-argument structures for event extraction in molecular biology
Background: The exploitation of information extraction (IE), a technology aiming to provide instances of structured representations from free-form text, has been rapidly growing w...
Tuangthong Wattarujeekrit, Parantu K. Shah, Nigel ...
BMCBI
2010
81views more  BMCBI 2010»
14 years 9 months ago
Empirical Bayes Analysis of Sequencing-based Transcriptional Profiling without Replicates
Background: Recent technological advancements have made high throughput sequencing an increasingly popular approach for transcriptome analysis. Advantages of sequencing-based tran...
Zhijin Wu, Bethany D. Jenkins, Tatiana A. Rynearso...