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» EDGE: extraction and analysis of differential gene expressio...
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BMCBI
2007
237views more  BMCBI 2007»
14 years 9 months ago
FLAME, a novel fuzzy clustering method for the analysis of DNA microarray data
Background: Data clustering analysis has been extensively applied to extract information from gene expression profiles obtained with DNA microarrays. To this aim, existing cluster...
Limin Fu, Enzo Medico
89
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BMCBI
2010
135views more  BMCBI 2010»
14 years 9 months ago
Delineation of amplification, hybridization and location effects in microarray data yields better-quality normalization
Background: Oligonucleotide arrays have become one of the most widely used high-throughput tools in biology. Due to their sensitivity to experimental conditions, normalization is ...
Marc Hulsman, Anouk Mentink, Eugene P. van Someren...
93
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BMCBI
2010
165views more  BMCBI 2010»
14 years 9 months ago
Filtering, FDR and power
Background: In high-dimensional data analysis such as differential gene expression analysis, people often use filtering methods like fold-change or variance filters in an attempt ...
Maarten van Iterson, Judith M. Boer, Renée ...
63
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RECOMB
2001
Springer
15 years 10 months ago
Analysis techniques for microarray time-series data
We address possible limitations of publicly available data sets of yeast gene expression. We study the predictability of known regulators via time-series analysis, and show that l...
Vladimir Filkov, Steven Skiena, Jizu Zhi
GECCO
2004
Springer
164views Optimization» more  GECCO 2004»
15 years 3 months ago
Fuzzy Dominance Based Multi-objective GA-Simplex Hybrid Algorithms Applied to Gene Network Models
Hybrid algorithms that combine genetic algorithms with the Nelder-Mead simplex algorithm have been effective in solving certain optimization problems. In this article, we apply a s...
Praveen Koduru, Sanjoy Das, Stephen Welch, Judith ...