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BMCBI
2007
127views more  BMCBI 2007»
14 years 10 months ago
Characterization of protein-interaction networks in tumors
Background: Analyzing differential-gene-expression data in the context of protein-interaction networks (PINs) yields information on the functional cellular status. PINs can be for...
Alexander Platzer, Paul Perco, Arno Lukas, Bernd M...
BMCBI
2008
131views more  BMCBI 2008»
14 years 10 months ago
Modifying the DPClus algorithm for identifying protein complexes based on new topological structures
Background: Identification of protein complexes is crucial for understanding principles of cellular organization and functions. As the size of protein-protein interaction set incr...
Min Li, Jianer Chen, Jianxin Wang, Bin Hu, Gang Ch...
BMCBI
2010
94views more  BMCBI 2010»
14 years 10 months ago
Comparison study of microarray meta-analysis methods
Background: Meta-analysis methods exist for combining multiple microarray datasets. However, there are a wide range of issues associated with microarray meta-analysis and a limite...
Anna Campain, Yee Hwa Yang
BMCBI
2010
110views more  BMCBI 2010»
14 years 10 months ago
GenHtr: a tool for comparative assessment of genetic heterogeneity in microbial genomes generated by massive short-read sequenci
Background: Microevolution is the study of short-term changes of alleles within a population and their effects on the phenotype of organisms. The result of the below-species-level...
GongXin Yu
BMCBI
2010
151views more  BMCBI 2010»
14 years 10 months ago
Using diffusion distances for flexible molecular shape comparison
Background: Many molecules are flexible and undergo significant shape deformation as part of their function, and yet most existing molecular shape comparison (MSC) methods treat t...
Yu-Shen Liu, Qi Li, Guo-Qin Zheng, Karthik Ramani,...