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» Efficient Multidimensional Sampling
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BMCBI
2007
144views more  BMCBI 2007»
14 years 10 months ago
Robust regression for periodicity detection in non-uniformly sampled time-course gene expression data
Background: In practice many biological time series measurements, including gene microarrays, are conducted at time points that seem to be interesting in the biologist's opin...
Miika Ahdesmäki, Harri Lähdesmäki, ...
BMCBI
2010
132views more  BMCBI 2010»
14 years 10 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
BMCBI
2008
119views more  BMCBI 2008»
14 years 10 months ago
A new method for 2D gel spot alignment: application to the analysis of large sample sets in clinical proteomics
Background: In current comparative proteomics studies, the large number of images generated by 2D gels is currently compared using spot matching algorithms. Unfortunately, differe...
Sabine Pérès, Laurence Molina, Nicol...
STOC
2006
ACM
122views Algorithms» more  STOC 2006»
15 years 10 months ago
Fast convergence to Wardrop equilibria by adaptive sampling methods
We study rerouting policies in a dynamic round-based variant of a well known game theoretic traffic model due to Wardrop. Previous analyses (mostly in the context of selfish routi...
Simon Fischer, Harald Räcke, Berthold Vö...
BMCBI
2006
113views more  BMCBI 2006»
14 years 10 months ago
GibbsST: a Gibbs sampling method for motif discovery with enhanced resistance to local optima
Background: Computational discovery of transcription factor binding sites (TFBS) is a challenging but important problem of bioinformatics. In this study, improvement of a Gibbs sa...
Kazuhito Shida