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BMCBI
2010
151views more  BMCBI 2010»
14 years 9 months ago
CCRaVAT and QuTie - enabling analysis of rare variants in large-scale case control and quantitative trait association studies
Background: Genome-wide association studies have been successful in finding common variants influencing common traits. However, these associations only account for a fraction of t...
Robert Lawrence, Aaron G. Day-Williams, Katherine ...
BMCBI
2008
242views more  BMCBI 2008»
14 years 9 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
CORR
2010
Springer
152views Education» more  CORR 2010»
14 years 9 months ago
Neuroevolutionary optimization
Temporal difference methods are theoretically grounded and empirically effective methods for addressing reinforcement learning problems. In most real-world reinforcement learning ...
Eva Volná
CPHYSICS
2010
184views more  CPHYSICS 2010»
14 years 9 months ago
Parallel Newton-Krylov-Schwarz algorithms for the three-dimensional Poisson-Boltzmann equation in numerical simulation of colloi
We investigate fully parallel Newton-Krylov-Schwarz (NKS) algorithms for solving the large sparse nonlinear systems of equations arising from the finite element discretization of ...
Feng-Nan Hwang, Shang-Rong Cai, Yun-Long Shao, Jon...
BMCBI
2006
113views more  BMCBI 2006»
14 years 9 months ago
QualitySNP: a pipeline for detecting single nucleotide polymorphisms and insertions/deletions in EST data from diploid and polyp
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
Jifeng Tang, Ben Vosman, Roeland E. Voorrips, C. G...