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» Efficient and Flexible Value Sampling
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BMCBI
2005
113views more  BMCBI 2005»
14 years 9 months ago
Pathway level analysis of gene expression using singular value decomposition
Background: A promising direction in the analysis of gene expression focuses on the changes in expression of specific predefined sets of genes that are known in advance to be rela...
John K. Tomfohr, Jun Lu, Thomas B. Kepler
KDD
2006
ACM
149views Data Mining» more  KDD 2006»
15 years 10 months ago
Regularized discriminant analysis for high dimensional, low sample size data
Linear and Quadratic Discriminant Analysis have been used widely in many areas of data mining, machine learning, and bioinformatics. Friedman proposed a compromise between Linear ...
Jieping Ye, Tie Wang
BMCBI
2011
14 years 4 months ago
Flexible taxonomic assignment of ambiguous sequencing reads
Background: To characterize the diversity of bacterial populations in metagenomic studies, sequencing reads need to be accurately assigned to taxonomic units in a given reference ...
José Carlos Clemente, Jesper Jansson, Gabri...
BMCBI
2010
132views more  BMCBI 2010»
14 years 9 months ago
Protein docking by Rotation-Based Uniform Sampling (RotBUS) with fast computing of intermolecular contact distance and residue d
Background: Protein-protein interactions are fundamental for the majority of cellular processes and their study is of enormous biotechnological and therapeutic interest. In recent...
Albert Solernou, Juan Fernández-Recio
ICS
2010
Tsinghua U.
15 years 7 months ago
Space-Efficient Estimation of Robust Statistics and Distribution Testing
: The generic problem of estimation and inference given a sequence of i.i.d. samples has been extensively studied in the statistics, property testing, and learning communities. A n...
Steve Chien, Katrina Ligett, Andrew McGregor