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BMCBI
2006
137views more  BMCBI 2006»
13 years 6 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...
BMCBI
2010
148views more  BMCBI 2010»
13 years 6 months ago
Applying unmixing to gene expression data for tumor phylogeny inference
Background: While in principle a seemingly infinite variety of combinations of mutations could result in tumor development, in practice it appears that most human cancers fall int...
Russell Schwartz, Stanley Shackney
CVPR
2007
IEEE
14 years 8 months ago
Regression tracking with data relevance determination
This paper 1 addresses the problem of efficient visual 2D template tracking in image sequences. We adopt a discriminative approach in which the observations at each frame yield di...
Ioannis Patras, Edwin R. Hancock
BMCBI
2008
163views more  BMCBI 2008»
13 years 6 months ago
The Annotation, Mapping, Expression and Network (AMEN) suite of tools for molecular systems biology
Background: High-throughput genome biological experiments yield large and multifaceted datasets that require flexible and user-friendly analysis tools to facilitate their interpre...
Frédéric Chalmel, Michael Primig
BMCBI
2010
112views more  BMCBI 2010»
13 years 6 months ago
Computational identification of rare codons of Escherichia coli based on codon pairs preference
Background: Codon bias is believed to play an important role in the control of gene expression. In Escherichia coli, some rare codons, which can limit the expression level of exog...
Xianming Wu, Songfeng Wu, Dong Li, Jiyang Zhang, L...