The vast number of expressed sequence tags (ESTs) in public databases provides an important resource for comparative and functional genomics. A variety of methods based on homology...
Motivation: Tumorigenesis is an evolutionary process by which tumor cells acquire sequences of mutations leading to increased growth, invasiveness, and eventually metastasis. It i...
David Tolliver, Charalampos E. Tsourakakis, Ayshwa...
Background: Orthology analysis is an important part of data analysis in many areas of bioinformatics such as comparative genomics and molecular phylogenetics. The ever-increasing ...
Next-generation high throughput sequencing instruments are capable of generating hundreds of millions of reads in a single run. Mapping those reads to a reference genome is an ext...
Similarity Matrix of Proteins (SIMAP) (http://mips.gsf. 10 de/simap) provides a database based on a precomputed similarity matrix covering the similarity space formed by .4 millio...
Roland Arnold, Thomas Rattei, Patrick Tischler, Mi...