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» Efficient computation of absent words in genomic sequences
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BMCBI
2010
116views more  BMCBI 2010»
14 years 9 months ago
Predicting success of oligomerized pool engineering (OPEN) for zinc finger target site sequences
Background: Precise and efficient methods for gene targeting are critical for detailed functional analysis of genomes and regulatory networks and for potentially improving the eff...
Jeffry D. Sander, Deepak Reyon, Morgan L. Maeder, ...
BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
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GECCO
2009
Springer
190views Optimization» more  GECCO 2009»
15 years 1 months ago
Genetic programming for protein related text classification
Since the genomics revolution, bioinformatics has never been so popular. Many researchers have investigated with great success the use of evolutionary computation in bioinformatic...
Marc Segond, Cyril Fonlupt, Denis Robilliard
BMCBI
2006
123views more  BMCBI 2006»
14 years 9 months ago
Computational models with thermodynamic and composition features improve siRNA design
Background: Small interfering RNAs (siRNAs) have become an important tool in cell and molecular biology. Reliable design of siRNA molecules is essential for the needs of large fun...
Svetlana A. Shabalina, Alexey N. Spiridonov, Aleks...
BMCBI
2011
14 years 4 months ago
SNiPlay: a web-based tool for detection, management and analysis of SNPs. Application to grapevine diversity projects
Background: High-throughput re-sequencing, new genotyping technologies and the availability of reference genomes allow the extensive characterization of Single Nucleotide Polymorp...
Alexis Dereeper, Stéphane Nicolas, Loic Le ...