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» Efficient computation of absent words in genomic sequences
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78
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BMCBI
2010
102views more  BMCBI 2010»
14 years 9 months ago
Missing genes in the annotation of prokaryotic genomes
Background: Protein-coding gene detection in prokaryotic genomes is considered a much simpler problem than in intron-containing eukaryotic genomes. However there have been reports...
Andrew S. Warren, Jeremy S. Archuleta, Wu-chun Fen...
BMCBI
2006
101views more  BMCBI 2006»
14 years 9 months ago
How repetitive are genomes?
Background: Genome sequences vary strongly in their repetitiveness and the causes for this are still debated. Here we propose a novel measure of genome repetitiveness, the index o...
Bernhard Haubold, Thomas Wiehe
79
Voted
CEC
2007
IEEE
15 years 1 months ago
Efficient assembling of genome fragments using genetic algorithm enhanced by heuristic search
Abstract-- Shotgun sequencing is the state-of-the-art to decode genome sequence. However this technique needs a lot of fragments. Combining those fragments correctly requires enorm...
Satoko Kikuchi, Goutam Chakraborty
RECOMB
2004
Springer
15 years 10 months ago
Finding approximate tandem repeats in genomic sequences
An efficient algorithm is presented for detecting approximate tandem repeats in genomic sequences. The algorithm is based on a flexible statistical model which allows a wide range...
Ydo Wexler, Zohar Yakhini, Yechezkel Kashi, Dan Ge...
76
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JCB
2007
78views more  JCB 2007»
14 years 9 months ago
Sorting by Reciprocal Translocations via Reversals Theory
The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of genome...
Michal Ozery-Flato, Ron Shamir