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» Efficient computation of absent words in genomic sequences
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BMCBI
2004
96views more  BMCBI 2004»
14 years 9 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2008
121views more  BMCBI 2008»
14 years 9 months ago
ReAlignerV: Web-based genomic alignment tool with high specificity and robustness estimated by species-specific insertion sequen
Background: Detecting conserved noncoding sequences (CNSs) across species highlights the functional elements. Alignment procedures combined with computational prediction of transc...
Hisakazu Iwama, Yukio Hori, Kensuke Matsumoto, Koj...
BMCBI
2011
14 years 4 months ago
PileLine: a toolbox to handle genome position information in next-generation sequencing studies
Background: Genomic position (GP) files currently used in next-generation sequencing (NGS) studies are always difficult to manipulate due to their huge size and the lack of approp...
Daniel Glez-Peña, Gonzalo Gómez-L&oa...
BMCBI
2007
139views more  BMCBI 2007»
14 years 9 months ago
XSTREAM: A practical algorithm for identification and architecture modeling of tandem repeats in protein sequences
Background: Biological sequence repeats arranged in tandem patterns are widespread in DNA and proteins. While many software tools have been designed to detect DNA tandem repeats (...
Aaron M. Newman, James B. Cooper
JCSS
2002
95views more  JCSS 2002»
14 years 9 months ago
Efficient algorithms for multichromosomal genome rearrangements
Hannenhalli and Pevzner [5] gave a polynomial time algorithm for computing the minimum number of reversals, translocations, fissions, and fusions, that would transform one multichr...
Glenn Tesler