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139
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BMCBI
2004
96views more  BMCBI 2004»
15 years 4 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2004
96views more  BMCBI 2004»
15 years 4 months ago
Identification of regions in multiple sequence alignments thermodynamically suitable for targeting by consensus oligonucleotides
Background: Computer programs for the generation of multiple sequence alignments such as "Clustal W" allow detection of regions that are most conserved among many sequen...
Olga V. Matveeva, Brian T. Foley, Vladimir A. Nemt...
BMCBI
2004
150views more  BMCBI 2004»
15 years 4 months ago
SS-Wrapper: a package of wrapper applications for similarity searches on Linux clusters
Background: Large-scale sequence comparison is a powerful tool for biological inference in modern molecular biology. Comparing new sequences to those in annotated databases is a u...
Chunlin Wang, Elliot J. Lefkowitz
BMCBI
2004
146views more  BMCBI 2004»
15 years 4 months ago
Multivariate search for differentially expressed gene combinations
Background: To identify differentially expressed genes, it is standard practice to test a twosample hypothesis for each gene with a proper adjustment for multiple testing. Such te...
Yuanhui Xiao, Robert D. Frisina, Alexander Gordon,...
163
Voted
CORR
2004
Springer
180views Education» more  CORR 2004»
15 years 4 months ago
Self-Organized Stigmergic Document Maps: Environment as a Mechanism for Context Learning
Social insect societies and more specifically ant colonies, are distributed systems that, in spite of the simplicity of their individuals, present a highly structured social organi...
Vitorino Ramos, Juan J. Merelo Guervós
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