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» Ensembl Genomes 2016: more genomes, more complexity
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BMCBI
2011
14 years 5 months ago
RAIphy: Phylogenetic classification of metagenomics samples using iterative refinement of relative abundance index profiles
Background: Computational analysis of metagenomes requires the taxonomical assignment of the genome contigs assembled from DNA reads of environmental samples. Because of the diver...
Ozkan U. Nalbantoglu, Samuel F. Way, Steven H. Hin...
BMCBI
2010
96views more  BMCBI 2010»
14 years 10 months ago
ModuleOrganizer: detecting modules in families of transposable elements
Background: Most known eukaryotic genomes contain mobile copied elements called transposable elements. In some species, these elements account for the majority of the genome seque...
Sébastien Tempel, Christine Rousseau, Fariz...
BIB
2007
108views more  BIB 2007»
14 years 10 months ago
Bayesian methods in bioinformatics and computational systems biology
Bayesian methods are valuable, inter alia, whenever there is a need to extract information from data that is uncertain or subject to any kind of error or noise (including measurem...
Darren J. Wilkinson
BMCBI
2004
102views more  BMCBI 2004»
14 years 10 months ago
FRAGS: estimation of coding sequence substitution rates from fragmentary data
Background: Rates of substitution in protein-coding sequences can provide important insights into evolutionary processes that are of biomedical and theoretical interest. Increased...
Estienne C. Swart, Winston A. Hide, Cathal Seoighe
BMCBI
2006
122views more  BMCBI 2006»
14 years 10 months ago
Computational reconstruction of transcriptional regulatory modules of the yeast cell cycle
Background: A transcriptional regulatory module (TRM) is a set of genes that is regulated by a common set of transcription factors (TFs). By organizing the genome into TRMs, a liv...
Wei-Sheng Wu, Wen-Hsiung Li, Bor-Sen Chen