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» Ensembl Genomes 2016: more genomes, more complexity
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BMCBI
2010
137views more  BMCBI 2010»
14 years 5 months ago
The ancient history of the structure of ribonuclease P and the early origins of Archaea
Background: Ribonuclease P is an ancient endonuclease that cleaves precursor tRNA and generally consists of a catalytic RNA subunit (RPR) and one or more proteins (RPPs). It repre...
Feng-Jie Sun, Gustavo Caetano-Anollés
BMCBI
2007
114views more  BMCBI 2007»
14 years 10 months ago
Combination of scoring schemes for protein docking
Background: Docking algorithms are developed to predict in which orientation two proteins are likely to bind under natural conditions. The currently used methods usually consist o...
Philipp Heuser, Dietmar Schomburg
COMPLEXITY
2004
165views more  COMPLEXITY 2004»
14 years 10 months ago
Sex promotes gamete selection: A quantitative comparative study of features favoring the evolution of sex
: Explaining the maintenance of sexual reproduction remains one of the greatest challenges in biology. The theoretical oddity of sex is based on at least three advantages that asex...
Klaus Jaffe
BMCBI
2010
167views more  BMCBI 2010»
14 years 10 months ago
Inference of sparse combinatorial-control networks from gene-expression data: a message passing approach
Background: Transcriptional gene regulation is one of the most important mechanisms in controlling many essential cellular processes, including cell development, cell-cycle contro...
Marc Bailly-Bechet, Alfredo Braunstein, Andrea Pag...
BMCBI
2007
160views more  BMCBI 2007»
14 years 10 months ago
Optimization based automated curation of metabolic reconstructions
Background: Currently, there exists tens of different microbial and eukaryotic metabolic reconstructions (e.g., Escherichia coli, Saccharomyces cerevisiae, Bacillus subtilis) with...
Vinay Satish Kumar, Madhukar S. Dasika, Costas D. ...