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» Ensembl Genomes 2016: more genomes, more complexity
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BMCBI
2008
119views more  BMCBI 2008»
14 years 10 months ago
Snagger: A user-friendly program for incorporating additional information for tagSNP selection
Background: There has been considerable effort focused on developing efficient programs for tagging single-nucleotide polymorphisms (SNPs). Many of these programs do not account f...
Christopher K. Edlund, Won H. Lee, Dalin Li, David...
BMCBI
2006
134views more  BMCBI 2006»
14 years 10 months ago
Application of machine learning in SNP discovery
Background: Single nucleotide polymorphisms (SNP) constitute more than 90% of the genetic variation, and hence can account for most trait differences among individuals in a given ...
Lakshmi K. Matukumalli, John J. Grefenstette, Davi...
CBMS
2004
IEEE
15 years 2 months ago
Toward a Systems Biology Software Toolkit
Insight to complex problems may be revealed when domain data sets are viewed or structured in new and innovative ways. Systems approaches to biomedical problems fundamentally invo...
Donald J. Johann, Michael D. McGuigan, Stanimire T...
BMCBI
2004
174views more  BMCBI 2004»
14 years 10 months ago
Implications for domain fusion protein-protein interactions based on structural information
Background: Several in silico methods exist that were developed to predict protein interactions from the copious amount of genomic and proteomic data. One of these methods is Doma...
Jer-Ming Chia, Prasanna R. Kolatkar
IJIT
2004
14 years 11 months ago
Computing Entropy for Ortholog Detection
Abstract-- Biological sequences from different species are called orthologs if they evolved from a sequence of a common ancestor species and they have the same biological function....
Hsing-Kuo Pao, John Case