159 search results - page 26 / 32 » Ensembl Genomes 2016: more genomes, more complexity |
95
Voted
BMCBI
2006
15 years 20 days ago
2006
Background: As biology becomes an increasingly computational science, it is critical that we develop software tools that support not only bioinformaticians, but also bench biologi...
125
Voted
BMCBI
2006
15 years 20 days ago
2006
Background: Single nucleotide polymorphisms (SNPs) are important tools in studying complex genetic traits and genome evolution. Computational strategies for SNP discovery make use...
90
Voted
BMCBI
2006
15 years 20 days ago
2006
Background: Gene function analysis often requires a complex and laborious sequence of laboratory and computer-based experiments. Choosing an effective experimental design generall...
122
Voted
BMCBI
2007
15 years 19 days ago
2007
Background: An important step in annotation of sequenced genomes is the identification of transcription factor binding sites. More than a hundred different computational methods h...
101
Voted
BMCBI
2010
15 years 23 days ago
2010
Background: Polymorphic variants and mutations disrupting canonical splicing isoforms are among the leading causes of human hereditary disorders. While there is a substantial evid...