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» Ensembl Genomes 2016: more genomes, more complexity
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HICSS
2003
IEEE
166views Biometrics» more  HICSS 2003»
15 years 3 months ago
Comparative Genome Annotation for Mapping, Prediction and Discovery of Genes
We have used comparative genome analyses to produce annotated maps for large genomic loci. The first example is a locus on mouse chromosome 9 that is syntenic to human chromosome ...
Claudia Kappen, J. Michael Salbaum
BIOCOMP
2007
14 years 11 months ago
xMAN: extreme MApping of oligoNucleotides
Background: The ability to rapidly map millions of oligonucleotide fragments to a reference genome is crucial to many high throughput genomic technologies. Results: We propose an ...
Wei Li, Jason S. Carroll, Myles Brown, X. Shirley ...
JCB
2007
78views more  JCB 2007»
14 years 10 months ago
Sorting by Reciprocal Translocations via Reversals Theory
The understanding of genome rearrangements is an important endeavor in comparative genomics. A major computational problem in this field is finding a shortest sequence of genome...
Michal Ozery-Flato, Ron Shamir
93
Voted
GECCO
2005
Springer
149views Optimization» more  GECCO 2005»
15 years 3 months ago
There's more to a model than code: understanding and formalizing in silico modeling experience
Mapping biology into computation has both a domain specific aspect – biological theory – and a methodological aspect – model development. Computational modelers have implici...
Janet Wiles, Nicholas Geard, James Watson, Kai Wil...
NAR
2011
256views Computer Vision» more  NAR 2011»
14 years 1 months ago
COSMIC: mining complete cancer genomes in the Catalogue of Somatic Mutations in Cancer
COSMIC (http://www.sanger.ac.uk/cosmic) curates comprehensive information on somatic mutations in human cancer. Release v48 (July 2010) describes over 136 000 coding mutations in ...
Simon A. Forbes, Nidhi Bindal, Sally Bamford, Char...