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» Ensembl Genomes 2016: more genomes, more complexity
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BMCBI
2008
155views more  BMCBI 2008»
14 years 10 months ago
Prediction of regulatory elements in mammalian genomes using chromatin signatures
Background: Recent genomic scale survey of epigenetic states in the mammalian genomes has shown that promoters and enhancers are correlated with distinct chromatin signatures, pro...
Kyoung-Jae Won, Iouri Chepelev, Bing Ren, Wei Wang
BMCBI
2008
104views more  BMCBI 2008»
14 years 10 months ago
ReRep: Computational detection of repetitive sequences in genome survey sequences (GSS)
Background: Genome survey sequences (GSS) offer a preliminary global view of a genome since, unlike ESTs, they cover coding as well as non-coding DNA and include repetitive region...
Thomas D. Otto, Leonardo H. F. Gomes, Marcelo Alve...
RECOMB
2007
Springer
15 years 10 months ago
GIMscan: A New Statistical Method for Analyzing Whole-Genome Array CGH Data
Genetic instability represents an important type of biological markers for cancer and many other diseases. Array Comparative Genome Hybridization (aCGH) is a high-throughput cytoge...
Yanxin Shi, Fan Guo, Wei Wu, Eric P. Xing
CORR
2000
Springer
112views Education» more  CORR 2000»
14 years 10 months ago
Evolution of differentiated expression patterns in digital organisms
Abstract. We investigate the evolutionary processes behind the development and optimization of multiple threads of execution in digital organisms using the avida platform, a softwa...
Charles Ofria, Christoph Adami, Travis C. Collier,...
RECOMB
2008
Springer
15 years 10 months ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...